Description

11-Keto Fluprostenol is a synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its high purity and structural specificity, enabling precise biochemical studies and the synthesis of more complex therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies focused on developing novel ophthalmic solutions and other prostaglandin-based therapies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced prostaglandin analogs for therapeutic use.
• Ophthalmic Research: Used in R&D for developing new drugs targeting glaucoma and ocular hypertension.
• Biochemical Studies: Serves as a reference standard and active agent in receptor binding assays and pharmacological profiling.
• Veterinary Medicine: Investigated for potential applications in animal health, particularly in reproductive management.
• Process Development: Employed in scaling up and optimizing synthetic routes for prostaglandin manufacturing.

Basic Information

Product Name	11-Keto Fluprostenol
CAS No.	62145-07-7
Molecular Formula	C₂₃H₂₉FO₆
Molecular Weight	420.47 g/mol
Synonyms	11-Oxo Fluprostenol; 9,11-Dideoxy-11-oxo-9α,11α-difluoro-15α-hydroxy-16-(3-trifluoromethylphenoxy)-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic Acid; 11-Keto-9,11-difluoro-15-hydroxy-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranorprosta-5Z,13E-dienoic Acid; Fluprostenol 11-Ketone; 11-Keto Fluprostenol Isopropyl Ester (related ester form); Prostaglandin F2α Analog; Latanoprost Intermediate
EINECS	Contact for details

Quality Control

Our 11-Keto Fluprostenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Assay	97.0% - 103.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.