Description

Anthroylouabain is a chemically modified derivative of the cardiac glycoside ouabain, distinguished by the introduction of an anthroyl fluorophore. This compound is of significant value as a high-affinity, fluorescent probe for the study of Na+/K+-ATPase enzyme activity and localization in biological research. It is primarily utilized by researchers and scientists in the fields of biochemistry, pharmacology, and cellular physiology for advanced mechanistic studies and diagnostic assay development.

Application

• Biochemical Research Probe: Used as a specific, fluorescent ligand for labeling and visualizing Na+/K+-ATPase in cell membranes.
• Enzyme Inhibition Studies: Employed in quantitative assays to study the kinetics and inhibition of the sodium-potassium pump.
• Cellular Physiology: Aids in investigating ion transport mechanisms, cell signaling pathways, and the role of digitalis-like compounds.
• Pharmaceutical Development: Serves as a tool compound in early-stage drug discovery for cardiovascular and neurological targets.
• Diagnostic Assay Development: Can be incorporated into fluorescence-based diagnostic kits for research purposes.

Basic Information

Product Name	Anthroylouabain
CAS No.	62026-02-2
Molecular Formula	C36H48N2O12
Molecular Weight	700.78 g/mol
Synonyms	9-Anthroylouabain; N-[9-(9-Anthroyloxy)nonyl]ouabain; 9-AO-Ouabain; Anthroyl Ouabain; Ouabain 9-anthroyl ester; Fluorescent Ouabain Derivative; Na+/K+-ATPase Fluorescent Probe
EINECS	Contact for details

Quality Control

Our Anthroylouabain is produced and handled under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to relevant industry standards for research chemicals, ensuring reliable performance in your experimental systems.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in DMSO, DMF; sparingly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.