Description

2,2,2-Trifluoro-n-Phenylacetimidoyl Chloride is a high-value, reactive trifluoromethylated building block used in advanced organic synthesis. This compound is critical for introducing the trifluoroacetimidoyl group, a key precursor for synthesizing nitrogen-containing heterocycles and complex molecules. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of nitrogen-containing heterocycles, such as imidazoles and triazoles, with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate the trifluoromethyl group for enhanced efficacy and stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of advanced polymers and functional organic materials with specific electronic or surface properties.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research focused on incorporating fluorine atoms into complex molecular architectures.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and APIs (Active Pharmaceutical Ingredients).

Basic Information

Item	Details
Product Name	2,2,2-Trifluoro-n-Phenylacetimidoyl Chloride
CAS No.	61881-19-4
Molecular Formula	C8H5ClF3N
Molecular Weight	207.58 g/mol
Synonyms	N-(2,2,2-Trifluoroacetyl)aniline Imidoyl Chloride; 2,2,2-Trifluoro-N-phenylacetimidoyl Chloride; α,α,α-Trifluoro-N-phenylacetimidoyl Chloride; Phenyl(trifluoroacetyl)imidoyl Chloride; Trifluoroacetophenone Imidoyl Chloride; TFPAIC; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-Phenylacetimidoyl Chloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.