Description

Prostacyclin Sodium Salt CAS NO 61849-14-7 is the stable, water-soluble sodium salt form of prostacyclin (PGI₂), a potent endogenous vasodilator and platelet aggregation inhibitor. This compound is a critical reference standard and active pharmaceutical ingredient (API) for cardiovascular and pulmonary research and therapeutic development. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing treatments for hypertension, pulmonary arterial hypertension (PAH), and thrombosis.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of prostacyclin-based drugs in research and quality control laboratories.
• Active Pharmaceutical Ingredient (API): Serves as the core component in the formulation of injectable medications for pulmonary arterial hypertension (PAH).
• Biochemical Research: A vital tool for studying vascular biology, platelet function, and the cyclooxygenase pathway in in vitro and ex vivo models.
• Cell Culture & Physiology Studies: Used to investigate its cytoprotective and anti-proliferative effects on endothelial and smooth muscle cells.
• Drug Discovery & Development: Employed in screening assays and preclinical studies for novel cardiovascular and anti-thrombotic therapeutics.

Basic Information

Product Name	Prostacyclin Sodium Salt
CAS No.	61849-14-7
Molecular Formula	C₂₀H₃₁NaO₅
Molecular Weight	374.45 g/mol
Synonyms	PGI₂ Sodium Salt; Epoprostenol Sodium Salt; 5Z,9α,11α,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic Acid Sodium Salt; Cycloprostin Sodium Salt; Sodium (5Z,9α,11α,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oate; Flolan® (brand name equivalent); Prostacyclin Na Salt
EINECS	Contact for details

Quality Control

Our Prostacyclin Sodium Salt is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.