Description

n-Butyl-n-(3-Oxobutyl)Nitrosamine is a specialized nitrosamine compound of significant interest in chemical research and development. This compound serves as a critical intermediate and reference standard in the study of nitrosamine formation, analysis, and toxicology. It is primarily utilized by research institutions and industrial laboratories focused on pharmaceutical safety, analytical method development, and regulatory compliance. Its well-defined structure makes it essential for calibrating sensitive detection equipment and validating processes to control nitrosamine impurities.

Application

• Analytical Reference Standard: Used for the calibration and validation of analytical methods (e.g., GC-MS, LC-MS/MS) for nitrosamine detection and quantification.
• Pharmaceutical Impurity Research: Serves as a model compound in studies investigating the formation, fate, and mitigation of nitrosamine impurities in active pharmaceutical ingredients (APIs) and drug products.
• Toxicological Studies: Employed in laboratory research to understand the metabolic pathways, genotoxicity, and carcinogenic potential of nitrosamine compounds.
• Method Development: Critical for developing and optimizing highly sensitive analytical procedures to meet stringent regulatory guidelines for nitrosamine limits in pharmaceuticals.
• Quality Control & Compliance: Used by quality control laboratories to ensure manufacturing processes and final products comply with global regulatory standards (e.g., FDA, EMA) regarding nitrosamine impurities.
• Chemical Synthesis Intermediate: Acts as a building block or precursor in specialized organic synthesis and chemical research programs.

Basic Information

Product Name	n-Butyl-n-(3-Oxobutyl)Nitrosamine
CAS No.	61734-90-5
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	N-Nitroso-N-butyl-4-oxobutan-1-amine; 4-Oxo-N-nitroso-N-butylbutan-1-amine; N-Butyl-N-(3-oxobutyl)nitrous amide; NB3OBNA; Butyl(3-oxobutyl)nitrosamine; N-Nitrosobutyl(3-oxobutyl)amine; N-Butyl-N-nitroso-4-oxobutan-1-amine
EINECS	Contact for details

Quality Control

Our n-Butyl-n-(3-Oxobutyl)Nitrosamine is produced and handled under strict quality management protocols. Each batch undergoes rigorous identity confirmation and purity analysis using advanced techniques such as HPLC, GC-MS, and NMR spectroscopy to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided with every shipment to support your traceability and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Yellow to brown liquid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.