Description

W-7 Hydrochloride is a high-purity, small-molecule chemical compound widely utilized in biochemical and pharmacological research. Its primary value lies in its function as a potent and selective inhibitor of calmodulin, making it an essential tool for studying calcium-mediated signaling pathways. This product is critical for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors who require reliable, high-quality biochemical reagents for target validation and mechanistic studies.

Application

• Biochemical Research: A key tool for investigating the role of calmodulin in cellular processes such as muscle contraction, neurotransmitter release, and cell cycle progression.
• Pharmaceutical R&D: Used in target identification and validation studies for diseases involving calcium signaling dysregulation, including neurological disorders and cardiovascular conditions.
• Enzyme Inhibition Studies: Serves as a specific calmodulin antagonist to study its interaction with various enzymes like phosphodiesterase and nitric oxide synthase.
• Cell Signaling Pathway Analysis: Employed in cell-based assays to dissect complex calcium/calmodulin-dependent signal transduction mechanisms.
• Academic Research: A standard reagent in university and institutional labs for fundamental research in cell biology and pharmacology.
• Diagnostic Development: Potential use in the development of biochemical assays and kits designed to measure calmodulin activity or screen for modulators.

Basic Information

Product Name	W-7 Hydrochloride
CAS No.	61714-27-0
Molecular Formula	C18H21ClN2O2 • HCl
Molecular Weight	369.29 g/mol
Synonyms	N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride; N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide HCl; Calmidazolium chloride (related compound, verify specific activity); W-7 HCl; Calmodulin inhibitor W-7 hydrochloride; 1-Naphthalenesulfonamide, N-(6-aminohexyl)-5-chloro-, hydrochloride; W-7 (hydrochloride)
EINECS	Contact for details

Quality Control

Our W-7 Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.