Description

2-Acetyl-1,2,3,4-Tetrahydroisoquinoline-7-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile intermediate for constructing complex molecules with specific biological or material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting the central nervous system or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, or insecticides by introducing the sulfonamide pharmacophore.
• Material Science Research: Serves as a monomer or cross-linking agent for creating specialty polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and protein interactions.
• Dye and Pigment Manufacturing: Intermediate for synthesizing specialized sulfonamide-based dyes and colorants.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring the introduction of a sulfonyl chloride functional group.

Basic Information

Product Name	2-Acetyl-1,2,3,4-Tetrahydroisoquinoline-7-Sulfonyl Chloride
CAS No.	61563-39-1
Molecular Formula	C11H12ClNO3S
Molecular Weight	273.73 g/mol
Synonyms	7-(Chlorosulfonyl)-2-acetyl-1,2,3,4-tetrahydroisoquinoline; 2-Acetyl-7-sulfonylchloride-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-2-acetylisoquinoline-7-sulfonyl chloride; ATIQ-SO2Cl; 7-Chlorosulfonyl-2-acetyl-1,2,3,4-tetrahydroisoquinoline; 2-Acetyl-1,2,3,4-tetrahydroisoquinoline-7-sulfonylchloride
EINECS	Contact for details

Quality Control

Our 2-Acetyl-1,2,3,4-Tetrahydroisoquinoline-7-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.