Description

7,8,9,10-Tetrahydroxy-7,8,9,10-Tetrahydrobenzo(A)Pyrene is a high-purity polycyclic aromatic hydrocarbon (PAH) derivative, specifically a tetrahydrotetrol metabolite of benzo(a)pyrene. This compound is of significant value in advanced research and analytical chemistry, serving as a critical reference standard and a key intermediate in metabolic and toxicological studies. It is primarily needed by research institutions, analytical laboratories, and pharmaceutical companies engaged in environmental monitoring, carcinogenicity research, and the development of detection methods for PAH metabolites.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the precise calibration of HPLC, GC-MS, and LC-MS/MS systems in the quantification of benzo(a)pyrene metabolites.
• Biomarker Research: Essential for studying DNA adduct formation and metabolic activation pathways of benzo(a)pyrene, a well-known carcinogen, in toxicology and cancer research.
• Environmental Monitoring: Employed in method development and validation for detecting and monitoring PAH exposure and metabolic profiles in environmental and biological samples.
• Pharmaceutical Intermediates: Acts as a sophisticated synthetic intermediate or a metabolite standard in the development of drugs targeting PAH-induced toxicity or related biochemical pathways.
• Academic & Industrial Research: Serves as a crucial reagent in fundamental chemical research exploring the reactivity, synthesis, and properties of polycyclic aromatic compounds.

Basic Information

Product Name	7,8,9,10-Tetrahydroxy-7,8,9,10-Tetrahydrobenzo(A)Pyrene
CAS No.	61490-67-3
Molecular Formula	C₂₀H₁₆O₄
Molecular Weight	320.34 g/mol
Synonyms	Benzo[a]pyrene-7,8,9,10-tetrahydrotetrol; (±)-7,8,9,10-Tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene; BP-7,8,9,10-tetrol; Benzo(a)pyrene trans-7,8,9,10-tetrahydrotetrol; r-7,t-8,9,c-10-Tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene; 7,8,9,10-Tetrahydrobenzo[a]pyrene-7,8,9,10-tetrol; B[a]P-7,8,9,10-tetrahydrotetrol
EINECS	Contact for details

Quality Control

Our 7,8,9,10-Tetrahydroxy-7,8,9,10-Tetrahydrobenzo(A)Pyrene is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive analytical and research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards, and our quality systems support the needs of research requiring reliable and traceable reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. The container should be kept in a cool, dry, and well-ventilated place, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.