Description

(7R,8S,9R,10S)-Rel-7,8,9,10-Tetrahydrobenzo[A]Pyrene-7,8,9,10-Tetrol is a high-purity, stereochemically defined polycyclic aromatic hydrocarbon (PAH) metabolite. This compound is of significant value as a critical reference standard and biochemical tool in environmental toxicology and metabolic pathway research. It is primarily needed by analytical laboratories, research institutions, and chemical manufacturers engaged in the study of PAH carcinogenesis, DNA adduct formation, and metabolic activation.

Application

• Analytical Reference Standard: Used as a primary standard for the quantification and identification of benzo[a]pyrene metabolites in complex matrices via HPLC, GC-MS, or LC-MS.
• Biochemical Research: Serves as a key intermediate in studies investigating the metabolic activation pathways of benzo[a]pyrene and its subsequent binding to DNA.
• Toxicology Studies: Employed in in vitro and in vivo assays to assess the mutagenic and carcinogenic potential of PAH exposure.
• Environmental Monitoring: Acts as a biomarker in environmental fate and exposure studies to track the metabolic processing of benzo[a]pyrene in biological systems.
• Pharmaceutical Development: Utilized in research focused on understanding and potentially inhibiting the enzymes responsible for PAH activation.
• Quality Control: Essential for the calibration and validation of analytical methods in laboratories performing regulatory or compliance testing for PAHs.

Basic Information

Product Name	(7R,8S,9R,10S)-Rel-7,8,9,10-Tetrahydrobenzo[A]Pyrene-7,8,9,10-Tetrol
CAS No.	61490-66-2
Molecular Formula	C₂₀H₁₆O₄
Molecular Weight	320.34 g/mol
Synonyms	Benzo[a]pyrene-7,8,9,10-tetrol; (±)-7,8,9,10-Tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene; BP-7,8,9,10-tetrol; B[a]P-7,8,9,10-tetrahydrotetrol; Benzo[a]pyrene tetrol; r-7,t-8,9,c-10-Tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene; Anti-Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide Hydrolysis Product
EINECS	Contact for details

Quality Control

Our (7R,8S,9R,10S)-Rel-7,8,9,10-Tetrahydrobenzo[A]Pyrene-7,8,9,10-Tetrol is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive analytical and research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods, and impurity profiles. We support compliance with relevant research and quality guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.