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9 Alpha,11 Alpha,15 α-Trihydroxy-16-Phenoxy-17,18,19,20-Tetranorprosta-4,5,13-Trienoic Acid CAS NO 61456-25-5


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CAS No.:61456-25-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

9 Alpha,11 Alpha,15 α-Trihydroxy-16-Phenoxy-17,18,19,20-Tetranorprosta-4,5,13-Trienoic Acid is a high-purity synthetic prostaglandin analog, a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its precise biological activity and structural complexity, enabling the development of targeted therapeutic agents. It is primarily needed by pharmaceutical R&D departments and fine chemical manufacturers specializing in prostaglandin-based drug discovery and production.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of prostaglandin-based drugs targeting ocular, cardiovascular, and gastrointestinal systems.
  • Biochemical Research: Used as a reference standard and active compound in pharmacological studies of prostaglandin receptors and signaling pathways.
  • Ophthalmic Drug Development: A precursor in the manufacturing of prostaglandin analogs used to treat glaucoma and ocular hypertension.
  • Fine Chemical Synthesis: Serves as a sophisticated chiral synthon for constructing complex, biologically active molecules in medicinal chemistry.
  • Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name 9 Alpha,11 Alpha,15 α-Trihydroxy-16-Phenoxy-17,18,19,20-Tetranorprosta-4,5,13-Trienoic Acid
CAS No. 61456-25-5
Molecular Formula C25H30O6
Molecular Weight 426.51 g/mol
Synonyms 9α,11α,15α-Trihydroxy-16-phenoxy-17,18,19,20-tetranorprosta-4,5,13-trien-1-oic acid; 16-Phenoxy Tetranor Prostaglandin E2; 16-Phenoxy Tetranor PGE2; 16-Phenoxy-ω-tetranor PGE2; 9,11,15-Trihydroxy-16-phenoxy-17,18,19,20-tetranorprosta-4,5,13-trien-1-oic acid; Prostaglandin E2 16-Phenoxy Tetranor Analog; AL-8810 (research code)
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Quality Control

Our 9 Alpha,11 Alpha,15 α-Trihydroxy-16-Phenoxy-17,18,19,20-Tetranorprosta-4,5,13-Trienoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with pharmaceutical-grade standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled temperature of 2-8°C to minimize oxidation and degradation. Due to its hygroscopic nature, the container must be kept in a dry environment with minimal exposure to ambient humidity. For long-term stability, storage at -20°C is recommended.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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