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9 Alpha,11 Alpha,15 α-Trihydroxy-16-Phenoxy-17,18,19,20-Tetranorprosta-4,5,13-Trienoic Acid CAS NO 61456-25-5
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CAS No.:61456-25-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
9 Alpha,11 Alpha,15 α-Trihydroxy-16-Phenoxy-17,18,19,20-Tetranorprosta-4,5,13-Trienoic Acid is a high-purity synthetic prostaglandin analog, a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its precise biological activity and structural complexity, enabling the development of targeted therapeutic agents. It is primarily needed by pharmaceutical R&D departments and fine chemical manufacturers specializing in prostaglandin-based drug discovery and production.
Application
- Pharmaceutical Intermediate: Key building block for the synthesis of prostaglandin-based drugs targeting ocular, cardiovascular, and gastrointestinal systems.
- Biochemical Research: Used as a reference standard and active compound in pharmacological studies of prostaglandin receptors and signaling pathways.
- Ophthalmic Drug Development: A precursor in the manufacturing of prostaglandin analogs used to treat glaucoma and ocular hypertension.
- Fine Chemical Synthesis: Serves as a sophisticated chiral synthon for constructing complex, biologically active molecules in medicinal chemistry.
- Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of active pharmaceutical ingredients (APIs).
Basic Information
| Product Name | 9 Alpha,11 Alpha,15 α-Trihydroxy-16-Phenoxy-17,18,19,20-Tetranorprosta-4,5,13-Trienoic Acid |
| CAS No. | 61456-25-5 |
| Molecular Formula | C25H30O6 |
| Molecular Weight | 426.51 g/mol |
| Synonyms | 9α,11α,15α-Trihydroxy-16-phenoxy-17,18,19,20-tetranorprosta-4,5,13-trien-1-oic acid; 16-Phenoxy Tetranor Prostaglandin E2; 16-Phenoxy Tetranor PGE2; 16-Phenoxy-ω-tetranor PGE2; 9,11,15-Trihydroxy-16-phenoxy-17,18,19,20-tetranorprosta-4,5,13-trien-1-oic acid; Prostaglandin E2 16-Phenoxy Tetranor Analog; AL-8810 (research code) |
| EINECS | Contact for details |
Quality Control
Our 9 Alpha,11 Alpha,15 α-Trihydroxy-16-Phenoxy-17,18,19,20-Tetranorprosta-4,5,13-Trienoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with pharmaceutical-grade standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and R&D documentation.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled temperature of 2-8°C to minimize oxidation and degradation. Due to its hygroscopic nature, the container must be kept in a dry environment with minimal exposure to ambient humidity. For long-term stability, storage at -20°C is recommended.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Related Substances (HPLC) | Total impurities ≤ 2.0% Any single impurity ≤ 0.5% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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