Description

9,17-Dibromo-11Beta,21-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-Acetate is a high-purity, halogenated steroid derivative with significant synthetic utility. This compound serves as a critical advanced intermediate in the multi-step synthesis of potent active pharmaceutical ingredients (APIs), particularly within the corticosteroid class. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development and production of specialized steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel or generic halogenated corticosteroid drugs.
• Steroid Research: Used in academic and industrial research to study structure-activity relationships (SAR) and develop new steroid analogs with modified biological activity.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex steroid molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Studies: Utilized as a probe or precursor in studies investigating steroid hormone receptors and metabolic pathways.

Basic Information

Product Name	9,17-Dibromo-11Beta,21-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-Acetate
CAS No.	61339-40-0
Molecular Formula	C₂₄H₂₈Br₂O₆
Molecular Weight	572.29 g/mol
Synonyms	9α,17α-Dibromo-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-acetate; 9,17-Dibromo-11β,21-dihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-acetate; 9α,17α-Dibromobetamethasone 21-acetate; 9,17-Dibromobetamethasone acetate; Betamethasone 9,17-dibromo derivative acetate ester; 16α-Methyl-9α,17α-dibromoprednisolone 21-acetate
EINECS	Contact for details

Quality Control

Our 9,17-Dibromo-11Beta,21-Dihydroxy-16Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.