Description

2H-Isoindole-2-Methanesulfonyl Chloride, 1,3-Dihydro-1,3-Dioxo- CAS NO 61271-03-2 is a high-purity, reactive sulfonyl chloride derivative of isoindole-1,3-dione (phthalimide). This compound serves as a critical versatile building block for the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life sciences industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing sulfonamide or sulfonate ester functional groups.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the phthalimide moiety is a common structural motif.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with specific thermal or chemical resistance properties.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and pigments.
• Bioconjugation & Probe Development: Useful in biochemical research for labeling proteins or other biomolecules due to its reactive sulfonyl chloride group.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services targeting niche or proprietary compounds.

Basic Information

Product Name	2H-Isoindole-2-Methanesulfonyl Chloride, 1,3-Dihydro-1,3-Dioxo-
CAS No.	61271-03-2
Molecular Formula	C9H6ClNO4S
Molecular Weight	259.66 g/mol
Synonyms	1,3-Dioxo-2H-isoindole-2-methanesulfonyl chloride; N-(Chlorosulfonylmethyl)phthalimide; Phthalimidomethanesulfonyl chloride; 2-(Chlorosulfonylmethyl)isoindoline-1,3-dione; NSC 163063; Phthalimido methanesulfonyl chloride; 1H-Isoindole-1,3(2H)-dione, 2-[(chlorosulfonyl)methyl]-
EINECS	Contact for details

Quality Control

Our production of 2H-Isoindole-2-Methanesulfonyl Chloride adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We are committed to consistent quality and supply reliability to support your critical R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.