Description

9-Deoxy-9-Methylene Prostaglandin E2 CAS NO 61263-32-9 is a synthetic prostaglandin analog, a key intermediate in the research and development of novel therapeutic agents. This compound is valued for its structural role in creating modified eicosanoids with targeted biological activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on metabolic, inflammatory, and ophthalmic drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of advanced prostaglandin-based drug candidates.
• Biochemical Research: Used in studies investigating prostaglandin receptor binding, signaling pathways, and structure-activity relationships (SAR).
• Ophthalmic Drug Development: Serves as a precursor for potential therapeutics targeting intraocular pressure and ocular blood flow.
• Metabolic Disorder Research: Employed in the development of compounds for studying lipid metabolism and related disorders.
• Inflammation & Pain Management R&D: A key synthon for creating novel anti-inflammatory and analgesic agents.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	9-Deoxy-9-Methylene Prostaglandin E2
CAS No.	61263-32-9
Molecular Formula	C21H34O5
Molecular Weight	366.5 g/mol
Synonyms	9-Deoxy-9-methylene PGE2; 9-Methylene-9-deoxyprostaglandin E2; 11α,15α-Dihydroxy-9-methylene-5-cis,13-trans-prostadienoic Acid; 9-Met-PGE2; 9-Deoxy-δ9-PGE2; Prostaglandin E2, 9-deoxy-9-methylene-; (5Z,13E)-(9R,11R,15S)-9-Methylene-11,15-dihydroxyprosta-5,13-dien-1-oic Acid
EINECS	Contact for details

Quality Control

Our 9-Deoxy-9-Methylene Prostaglandin E2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements of pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened vials at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Store away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.