Description

16-Methyl-20-Methoxy-Pge2 CAS NO 61218-31-3 is a high-purity synthetic prostaglandin E2 (PGE2) analog, distinguished by its specific methyl and methoxy substitutions. This compound is valued for its potent biological activity and serves as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily needed by research institutions, pharmaceutical manufacturers, and biotechnology companies focused on developing novel therapeutics in areas such as inflammation, immunology, and reproductive health.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel prostaglandin-based drugs targeting inflammation, pain, and gastrointestinal disorders.
• Biochemical Research: Used as a reference standard and active agent in cell signaling studies, receptor binding assays, and pharmacological research.
• Drug Discovery & Development: Serves as a lead compound or a structural template for medicinal chemistry programs aimed at modulating prostaglandin pathways.
• Academic Research: Employed in university and institutional labs for studying the physiological and pathological roles of eicosanoids.
• Quality Control & Analytical Standards: Utilized as a certified reference material (CRM) for method development and validation in analytical laboratories.

Basic Information

Product Name	16-Methyl-20-Methoxy-Pge2
CAS No.	61218-31-3
Molecular Formula	C23H38O6
Molecular Weight	410.55 g/mol
Synonyms	16-Methyl-20-methoxyprostaglandin E2; 16-Methyl-20-methoxy-PGE2; 16-Methyl-20-O-methyl-PGE2; 11α,15α-Dihydroxy-16-methyl-20-methoxy-9-oxoprosta-5,13-dien-1-oic acid; 16-Methyl-20-methoxy-dinoprostone; 16-Me-20-OMe-PGE2; Prostaglandin E2, 16-methyl-20-methoxy-
EINECS	Contact for details

Quality Control

Our 16-Methyl-20-Methoxy-Pge2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purification to meet specific pharmacopeial or internal standards (e.g., >98% purity) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term stability, store in a dedicated, temperature-monitored freezer.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.