Description

2-Bromo-1-(Bromomethyl)-4-Fluorobenzene is a versatile and highly functionalized halogenated aromatic building block. Its unique structure, featuring both bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules in advanced chemical synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to introduce specific halogenated motifs that can dramatically alter the biological activity and physical properties of target compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-cancer agents, and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine atoms contribute to enhanced efficacy and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated and brominated organic compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to create complex biaryl and other conjugated structures.
• Functional Material Research: Employed in academic and industrial R&D for developing novel polymers, ligands for catalysis, and specialty chemicals with tailored properties.
• Derivatization for Analytical Standards: Used to prepare reference standards and metabolites for analytical method development and validation in regulatory testing.

Basic Information

Product Name	2-Bromo-1-(Bromomethyl)-4-Fluorobenzene
CAS No.	61150-57-0
Molecular Formula	C7H5Br2F
Molecular Weight	267.92 g/mol
Synonyms	1,2-Dibromo-4-Fluorotoluene; 4-Fluoro-1,2-bis(bromomethyl)benzene; 2-Bromo-α-bromo-4-fluorotoluene; 4-Fluoro-o-xylylene dibromide; α,2-Dibromo-4-fluorotoluene; 1-(Bromomethyl)-2-bromo-4-fluorobenzene; (2-Bromo-4-fluorophenyl)dibromomethane
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(Bromomethyl)-4-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤3.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.