Description

Butanedioic Acid-2,3-13C2 is a stable isotope-labeled analog of succinic acid, where two carbon atoms at the 2 and 3 positions are replaced with the carbon-13 isotope. This compound is essential for advanced analytical and metabolic research, providing a critical internal standard for precise quantification and pathway tracing. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for applications in mass spectrometry, NMR spectroscopy, and metabolic flux analysis.

Application

• Internal Standard for Quantitative Analysis: Used as a reference standard in LC-MS and GC-MS for the accurate quantification of endogenous succinic acid in complex biological matrices.
• Metabolic Pathway Tracing: Enables the study of metabolic fluxes in central carbon metabolism, including the TCA cycle, in cell cultures, tissues, and whole organisms.
• Pharmaceutical Research: Facilitates drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules and their metabolites.
• Biochemical Assay Development: Serves as a critical component in developing and validating diagnostic assays and enzymatic activity tests.
• Nutritional and Clinical Research: Used in tracer studies to investigate metabolic disorders, energy metabolism, and nutritional interventions.
• Agrochemical Research: Applied in plant and soil science to study plant respiration, stress responses, and nutrient assimilation pathways.

Basic Information

Product Name	Butanedioic Acid-2,3-13C2
CAS No.	61128-08-3
Molecular Formula	C213C2H6O4
Molecular Weight	120.07 g/mol (for 13C2 labeled form)
Synonyms	Succinic Acid-2,3-13C2; [2,3-13C2]Succinic Acid; 1,4-Butanedioic Acid-2,3-13C2; Butanedioic-2,3-13C2 Acid; Amber Acid-2,3-13C2; Ethylenesuccinic Acid-2,3-13C2; 1,2-Ethanedicarboxylic Acid-2,3-13C2; Dihydrofumaric Acid-2,3-13C2
EINECS	Contact for details

Quality Control

Our Butanedioic Acid-2,3-13C2 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity for research applications. Each batch is characterized by advanced analytical techniques including NMR and high-resolution mass spectrometry to confirm isotopic enrichment and positional labeling. Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and specific analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (13C)	≥ 99 atom % 13C
Isotopic Enrichment (Position 2 & 3)	≥ 99%
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.