Description

Papulacandin B is a potent antifungal agent belonging to the papulacandin class of glycolipid antibiotics. This compound is of significant interest in biochemical and pharmaceutical research due to its specific mechanism of action, which involves the inhibition of β-(1,3)-glucan synthase, a key enzyme in fungal cell wall synthesis. It serves as a critical reference standard and research tool for scientists in antifungal drug discovery, microbiology, and cell biology.

Application

• Antifungal Research & Drug Discovery: Used as a biochemical tool to study fungal cell wall biosynthesis and screen for novel antifungal compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical R&D.
• Mechanistic Studies: Employed in academic and industrial laboratories to investigate the function and inhibition of β-(1,3)-glucan synthase.
• Microbiological Assays: Utilized in in vitro assays to determine the susceptibility of pathogenic fungi and study resistance mechanisms.

Basic Information

Product Name	Papulacandin B
CAS No.	61032-80-2
Molecular Formula	C46H74O17
Molecular Weight	899.07 g/mol
Synonyms	Papulacandin B; Antibiotic SL 2266; Antibiotic 2266; Papulacandin; (1R,2S,3R,1'R,2'S)-2-[(2',3'-Dihydroxy-1'-hydroxymethyltetradecyl)oxy]-1,3,4-trihydroxy-5-[4-hydroxy-3-(tetracosanoyloxy)benzyl]-7-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid γ-lactone
EINECS	Contact for details

Quality Control

Our Papulacandin B is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.