Description

Hydroxyfenofibric Acid CAS NO 61002-27-5 is a key pharmaceutical intermediate and active metabolite of fenofibrate, a widely used lipid-regulating agent. This compound is critical for the research, development, and quality control of fibrate-class drugs, ensuring efficacy and safety in therapeutic applications. It serves as a vital building block for pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories focused on cardiovascular and metabolic disease treatments.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of fenofibrate and related fibrate derivatives.
• Reference Standard: Serves as a high-purity chemical standard for HPLC, LC-MS, and other analytical methods in drug quality control and pharmacokinetic studies.
• Metabolite Research: Used in clinical and preclinical research to study the metabolism, activity, and safety profile of fenofibrate.
• Active Pharmaceutical Ingredient (API) Development: A crucial starting material in the development and scale-up of new lipid-modulating therapies.
• Biochemical Research: Employed in vitro studies to investigate mechanisms of action on peroxisome proliferator-activated receptors (PPARs).

Basic Information

Product Name	Hydroxyfenofibric Acid
CAS No.	61002-27-5
Molecular Formula	C17H15ClO4
Molecular Weight	318.75 g/mol
Synonyms	2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic Acid; 1-Methylethyl 2-[4-[(4-chlorophenyl)carbonyl]phenoxy]-2-methylpropanoate Impurity; Fenofibric Acid Metabolite; CP-778; Isofibrate Metabolite; Hydroxy Fenofibric Acid; 4'-Hydroxyfenofibric Acid
EINECS	Contact for details

Quality Control

Our Hydroxyfenofibric Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and GC. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with the stringent requirements of pharmaceutical development and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.