Description

Gonyautoxin I is a potent neurotoxin belonging to the saxitoxin family, a group of naturally occurring compounds produced by certain marine dinoflagellates. This high-purity reference standard is critical for analytical research, toxicological studies, and the development of detection methods for paralytic shellfish poisoning (PSP). It is primarily utilized by research institutions, diagnostic laboratories, and regulatory bodies involved in marine biotoxin monitoring and food safety programs.

Application

• Analytical Reference Standard: Primary use as a certified standard for the precise calibration and validation of analytical instruments like HPLC, LC-MS, and ELISA kits used in toxin detection.
• Toxicological Research: Essential for studying the mechanism of action, potency, and metabolic pathways of saxitoxin analogues in both in vitro and in vivo models.
• Diagnostic Development: Key component in the research, development, and quality control of rapid test kits and biosensors for monitoring shellfish safety.
• Regulatory Compliance & Monitoring: Supports national and international food safety agencies in establishing and enforcing regulatory limits for PSP toxins in seafood.
• Pharmaceutical Research: Investigated in neurological studies for its highly specific interaction with voltage-gated sodium channels.
• Environmental Monitoring: Used in oceanographic and ecological studies to track harmful algal blooms (HABs) and assess ecosystem toxicity.

Basic Information

Product Name	Gonyautoxin I
CAS No.	60748-39-2
Molecular Formula	C10H17N7O8
Molecular Weight	347.29 g/mol
Synonyms	GTX1; Gonyautoxin 1; 11-Hydroxysaxitoxin; 11-Hydroxy-STX; (3aS,4R,9aS)-2,6-Diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-1H,10H-pyrrolo[1,2-c]purine-9,9,10-triol; Saxitoxin congener GTX1; PSP Toxin GTX1
EINECS	Contact for details

Quality Control

Our Gonyautoxin I is produced and handled under strict quality protocols to ensure identity, purity, and stability. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from advanced analytical techniques. We adhere to ISO 17034 guidelines for reference material production, ensuring traceability and reliability for critical research and regulatory applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation. The product is strictly light-sensitive and must be protected from all light exposure during handling and storage.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area Percent)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0% w/w
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.