Description

H-D-Phe-Pro-Arginal is a potent and highly specific synthetic tripeptide aldehyde that functions as a selective serine protease inhibitor. This compound is of significant value in biochemical research and pharmaceutical development due to its role in studying enzymatic pathways related to blood coagulation, fibrinolysis, and cellular signaling. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in the development of novel therapeutic agents and analytical reagents. The product is supplied as a high-purity reference standard to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a critical tool compound for studying the mechanism and inhibition of serine proteases like thrombin, trypsin, and related enzymes.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the R&D of anticoagulant and antithrombotic drugs.
• Diagnostic Reagents: Employed in the formulation of in-vitro diagnostic (IVD) kits for clinical assays measuring coagulation parameters.
• Enzyme Kinetics: Acts as a reversible, active-site directed inhibitor for detailed kinetic analysis and characterization of protease activity.
• Cell Biology Studies: Utilized to investigate protease-mediated cellular processes, including apoptosis and signal transduction pathways.

Basic Information

Product Name	H-D-Phe-Pro-Arginal
CAS No.	60503-05-1
Molecular Formula	C20H30N6O3
Molecular Weight	402.49 g/mol
Synonyms	D-Phenylalanyl-L-prolyl-L-argininal; (R)-2-((S)-1-((S)-4-Amino-1-formylbutylcarbamoyl)pyrrolidin-2-yl)-3-phenylpropanoic acid; Phe-Pro-Arg-H; Thrombin Inhibitor I; MDL 101,753; Benzyloxycarbonyl-D-Phe-Pro-Arginal derivative; D-Phe-Pro-Arginal
EINECS	Contact for details

Quality Control

Our H-D-Phe-Pro-Arginal is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is subjected to comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to guarantee product integrity and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.