Description

Sulprostone is a synthetic prostaglandin E2 (PGE2) analog, a potent and selective EP1/EP3 receptor agonist. This compound is of significant value in biochemical and pharmacological research for its role in studying smooth muscle contraction, uterine physiology, and receptor-mediated signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and contract research organizations (CROs) focused on reproductive health, gastroenterology, and cardiovascular systems.

Application

• Pharmacological Research: A key tool for investigating the physiological and pathophysiological roles of prostaglandin receptors, particularly EP1 and EP3 subtypes.
• Smooth Muscle Studies: Used in in vitro and ex vivo models to study contraction mechanisms in uterine, gastrointestinal, and vascular tissues.
• Drug Discovery & Development: Serves as a reference standard or active pharmaceutical ingredient (API) intermediate in the development of novel therapeutics targeting prostaglandin pathways.
• Academic & Clinical Research: Employed in studies related to labor induction, cervical ripening, and other reproductive health applications.
• Biochemical Assay Development: Used as a ligand in receptor binding assays and functional tests to screen for agonists or antagonists.

Basic Information

Product Name	Sulprostone
CAS No.	60325-46-4
Molecular Formula	C₂₃H₃₁NO₆S
Molecular Weight	449.56 g/mol
Synonyms	N-Methylsulprostone; 7-[3-Hydroxy-2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide; ZK 57671; SH B 286; ZK-57671; ZK57671; (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxy-4-phenoxy-1-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)hept-5-enamide
EINECS	Contact for details

Quality Control

Our Sulprostone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets high-purity research standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.