Description

2,6-Difluorobenzenesulfonyl Chloride is a high-purity, reactive organofluorine building block essential for advanced chemical synthesis. This compound serves as a critical precursor for introducing the 2,6-difluorobenzenesulfonyl moiety, a key structural motif in modern agrochemical and pharmaceutical development. It is primarily utilized by R&D chemists and process engineers in the fine chemical, pharmaceutical, and crop protection industries for creating novel sulfonamides and other functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of modern herbicides, fungicides, and insecticides, where the difluoro-substituted sulfonyl group enhances biological activity and environmental stability.
• Material Science Research: Employed in the creation of specialized polymers, liquid crystals, and advanced organic electronic materials requiring fluorinated aromatic components.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of chemical probes targeting specific enzymes or biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and development candidates.

Basic Information

Product Name	2,6-Difluorobenzenesulfonyl Chloride
CAS No.	60230-36-6
Molecular Formula	C6H3ClF2O2S
Molecular Weight	212.60 g/mol
Synonyms	2,6-Difluorobenzenesulfonyl chloride; Benzenesulfonyl chloride, 2,6-difluoro-; 2,6-Difluorophenylsulfonyl chloride; 2,6-Difluorobenzene-1-sulfonyl chloride; 60230-36-6; 2,6-DFBS-Cl; 2,6-Difluoro-benzenesulfonylchlorid
EINECS	Contact for details

Quality Control

Our 2,6-Difluorobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.