Description

4-o-Deacetylvinblastine-3-Oic Acid is a key vinca alkaloid derivative and an important pharmaceutical intermediate. This compound is valued for its role in the synthesis and research of complex bioactive molecules, particularly in oncology. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in anticancer drug development and natural product chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the semi-synthesis of complex anticancer agents and other therapeutic vinca alkaloids.
• Research & Development: Used in biochemical and pharmacological research to study structure-activity relationships (SAR) of vinca alkaloid derivatives.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Studies: Employed in university and institutional research for exploring novel synthetic pathways and natural product modifications.
• Process Chemistry: Utilized in scaling up and optimizing synthetic routes for the production of advanced pharmaceutical ingredients (APIs).

Basic Information

Product Name	4-o-Deacetylvinblastine-3-Oic Acid
CAS No.	60223-75-8
Molecular Formula	C44H54N4O9
Molecular Weight	782.93 g/mol
Synonyms	4-O-Deacetylvinblastine-3-carboxylic Acid; 3-Carboxyvinblastine; Deacetylvinblastine Acid; 4-Desacetylvinblastine-3-carboxylic Acid; NSC 682245; Vinblastine-3-carboxylic Acid; 4-O-Deacetylvinblastine Acid; 4-Desacetylvinblastine Acid
EINECS	Contact for details

Quality Control

Our 4-o-Deacetylvinblastine-3-Oic Acid is produced and tested under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a dry environment and opened under conditions of low humidity to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.