Description

Prostaglandin J2 CAS NO 60203-57-8 is a bioactive cyclopentenone prostaglandin that serves as a potent signaling molecule in cellular processes. It is valued for its role as a mediator of oxidative stress response and as a ligand for specific nuclear receptors, making it a critical tool for biochemical research. This compound is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on inflammation, apoptosis, and metabolic pathway studies.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of cellular signaling, oxidative stress, and inflammation pathways.
• Pharmaceutical Development: Investigated for its potential therapeutic roles in metabolic disorders, neurodegenerative diseases, and cancer research.
• Cell Biology Studies: Employed to study mechanisms of apoptosis (programmed cell death) and cellular differentiation.
• Enzyme Activity Modulation: Acts as a substrate or modulator in enzymatic studies related to prostaglandin metabolism.
• Receptor Binding Assays: Utilized as a high-affinity ligand for research on peroxisome proliferator-activated receptors (PPARs) and other nuclear receptors.
• Metabolomics and Lipidomics: Serves as an important analyte in the profiling of eicosanoids and related lipid mediators.

Basic Information

Product Name	Prostaglandin J2
CAS No.	60203-57-8
Molecular Formula	C20H28O4
Molecular Weight	332.44 g/mol
Synonyms	PGJ2; 15-Deoxy-δ12,14-prostaglandin J2; 15-Deoxy-δ-12,14-PGJ2; 15d-PGJ2; 9,10-Didehydro-15-deoxy-δ12,14-PGJ2; (5Z,9α,11α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic acid; 15-Deoxy-δ12,14-prostaglandin J2
EINECS	Contact for details

Quality Control

Our Prostaglandin J2 is produced under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive and easily oxidized; allow it to reach room temperature in the sealed container before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.