Description

Benzenesulfonylfluoride, 3,4-Dichloro- is a specialized organosulfur compound featuring a reactive sulfonyl fluoride group flanked by chlorine substituents. This molecular architecture makes it a valuable high-purity building block and reagent in advanced synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for constructing complex molecules and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of sulfonamide-based drug candidates and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides that incorporate sulfonyl fluoride or sulfonamide moieties.
• Chemical Biology & Proteomics: Serves as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Organic Synthesis Reagent: Utilized in Suzuki-Miyaura and other cross-coupling reactions to introduce the 3,4-dichlorophenylsulfonyl group.
• Fluorination Agent: Acts as a source of the sulfonyl fluoride functional group in modular synthesis workflows.

Basic Information

Item	Detail
Product Name	Benzenesulfonylfluoride, 3,4-Dichloro-
CAS No.	60191-50-6
Molecular Formula	C6H3Cl2FO2S
Molecular Weight	229.06 g/mol
Synonyms	3,4-Dichlorobenzenesulfonyl Fluoride; 3,4-Dichlorophenylsulfonyl Fluoride; 1,2-Dichloro-4-(fluorosulfonyl)benzene; 3,4-Dichlorobenzene-1-sulfonyl Fluoride; (3,4-Dichlorophenyl)sulfonyl Fluoride; 3,4-Dichloro Benzenesulfonylfluoride; 3,4-DCBSF
EINECS	Contact for details

Quality Control

Our production of Benzenesulfonylfluoride, 3,4-Dichloro- adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the exacting standards required for GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.