Description

Thromboxane A3 is a bioactive eicosanoid and a member of the thromboxane family, a critical class of lipid mediators derived from arachidonic acid metabolism. This compound is of significant interest in biochemical and pharmacological research due to its distinct biological activity profile compared to other thromboxanes, particularly in platelet aggregation and vascular function studies. It serves as an essential reference standard and research chemical for scientists in pharmaceutical R&D, cardiovascular research, and molecular biology, enabling the study of eicosanoid signaling pathways and the development of targeted therapeutics.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of eicosanoid biosynthesis, metabolism, and receptor interactions.
• Pharmacological Studies: Critical for investigating the role of thromboxanes in platelet aggregation, vasoconstriction, and inflammation to identify new drug targets.
• Analytical Method Development: Serves as a certified standard for calibrating analytical equipment (e.g., LC-MS, HPLC) in bioanalytical laboratories.
• Cell Signaling & Pathway Analysis: Employed in cell-based assays to elucidate downstream effects of thromboxane receptor activation and related signal transduction mechanisms.
• Academic Research: Utilized in university and institutional labs for fundamental research in lipidomics, physiology, and cardiovascular disease models.

Basic Information

Product Name	Thromboxane A3
CAS No.	60114-68-3
Molecular Formula	C20H32O5
Molecular Weight	352.47 g/mol
Synonyms	TXA3; (5Z,9α,11α,13E,15S)-9,11-Epoxy-15-hydroxythromboxa-5,13-dien-1-oic acid; Thromboxane A3; 9,11-Epithio-11,12-seco-thromboxane A2 (related analog); 15-Hydroxy-9,11-epoxythromboxa-5,13-dien-1-oic acid
EINECS	Contact for details

Quality Control

Our Thromboxane A3 is produced and handled under strict quality protocols to ensure the integrity and purity required for sensitive research applications. Each batch undergoes comprehensive analytical characterization, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. The material is highly volatile and light-sensitive; allow the vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.