Description

Cinobufotoxin is a potent steroidal cardiotonic glycoside and bufadienolide compound derived from toad venom. This high-purity biochemical is valued for its significant pharmacological activity and serves as a critical reference standard and active pharmaceutical ingredient (API) in research and development. It is essential for pharmaceutical manufacturers, biotechnology research laboratories, and academic institutions focused on oncology, cardiology, and novel drug discovery.

Application

• Pharmaceutical API Development: Serves as a key active ingredient in the research and formulation of anticancer and cardiotonic drugs.
• Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method validation in pharmaceutical testing.
• Biomedical Research: Employed in in vitro and in vivo studies to investigate mechanisms of action related to cell proliferation, apoptosis, and cardiac function.
• Traditional Medicine Modernization: A vital component in the scientific standardization of traditional Chinese medicine (TCM) preparations containing toad venom.
• Preclinical Studies: Utilized in pharmacological and toxicological evaluations during the drug discovery pipeline.

Basic Information

Product Name	Cinobufotoxin
CAS No.	60113-07-7
Molecular Formula	C40H60N4O10
Molecular Weight	756.93 g/mol
Synonyms	Bufotoxin; Cinobufagin 3-suberoylarginine ester; Ch'an Su; Toad Venom Toxin; Bufotalin-3-suberoylarginine ester; Arenobufagin 3-suberoylarginine ester; Gamabufotalin 3-suberoylarginine ester
EINECS	Contact for details

Quality Control

Our Cinobufotoxin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for pharmaceutical reference standards, and our quality protocols are designed to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.