Description

6-Oxo-5,9-Dihydropurine-8-Sulfonyl Fluoride is a high-value, reactive sulfonyl fluoride derivative of a purine scaffold, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its ability to act as a versatile electrophile for the selective modification of biomolecules and the construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science, where precise molecular engineering is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel purine-based drug candidates, including kinase inhibitors and antiviral agents.
• Bioconjugation & Probe Development: Utilized in chemical biology for the selective labeling of proteins, enzymes, and other biomolecules via SuFEx (Sulfur(VI) Fluoride Exchange) click chemistry.
• Agrochemical Research: Building block for creating new active ingredients with potential herbicidal or pesticidal activity.
• Material Science: Used in the development of specialty polymers and functionalized surfaces.
• Chemical Biology Tool: Acts as an activity-based probe (ABP) to study enzyme function and mechanism in complex biological systems.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening campaigns.

Basic Information

Item	Details
Product Name	6-Oxo-5,9-Dihydropurine-8-Sulfonyl Fluoride
CAS No.	6961-29-1
Molecular Formula	C5H3FN4O3S
Molecular Weight	218.16 g/mol
Synonyms	8-Sulfonylfluoride-6-oxo-5,9-dihydropurine; Purine-8-sulfonyl fluoride, 1,4,5,6-tetrahydro-6-oxo-; 1H-Purine-8-sulfonyl fluoride, 1,4,5,6-tetrahydro-6-oxo-; 6-Oxo-1,4,5,6-tetrahydro-purine-8-sulfonyl fluoride; 8-Purinesulfonyl fluoride, 1,4,5,6-tetrahydro-6-oxo-; 6-Oxo-5,9-dihydro-8-purinesulfonyl fluoride
EINECS	Contact for details

Quality Control

Our 6-Oxo-5,9-Dihydropurine-8-Sulfonyl Fluoride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.