Description

Coralyne CAS NO 6872-73-7 is a synthetic alkaloid compound belonging to the protoberberine class, known for its distinctive planar structure and biological activity. This compound is valued in research and development for its role as a potent topoisomerase inhibitor and its ability to interact with nucleic acids, particularly G-quadruplex structures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in anticancer drug discovery, biochemical studies, and as a reference standard.

Application

• Anticancer Research: Investigated as a lead compound for the development of novel chemotherapeutic agents due to its topoisomerase I and II inhibition properties.
• Biochemical Probe: Used in molecular biology to study DNA and RNA interactions, specifically the stabilization of G-quadruplex DNA structures, which are relevant in telomere biology and gene regulation.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Apoptosis Induction Studies: Employed in cell biology research to study pathways of programmed cell death in various cancer cell lines.
• Antimicrobial Screening: Evaluated for potential antibacterial and antifungal activities in microbiological research programs.

Basic Information

Product Name	Coralyne
CAS No.	6872-73-7
Molecular Formula	C21H21NO4
Molecular Weight	351.40 g/mol
Synonyms	Coralyne; NSC-154890; 8,13,13a,14-Tetrahydro-3,10,11-trimethoxy-5-methyl-6H-dibenzo[a,g]quinolizinium; Coralyne chloride; Sanguinarine analog; 3,10,11-Trimethoxy-5-methyl-6H-dibenzo[a,g]quinolizinium
EINECS	Contact for details

Quality Control

Our Coralyne is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, identification by spectroscopic methods, and control of residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications. We support research and development with material suitable for use as a reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.