Description

(3S,4R,5S,6R)-3-Amino-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2,4,5-Triol Hydrochloride is a high-purity, chiral amino sugar derivative, serving as a critical building block in advanced pharmaceutical synthesis. Its value lies in its role as a key intermediate for the development of glycosidase inhibitors, antiviral agents, and complex carbohydrate-based therapeutics. This compound is essential for research institutions and pharmaceutical manufacturers focused on metabolic disease treatments, antiviral drugs, and novel glycobiology applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of glycosidase inhibitors like miglitol and voglibose, used in diabetes management.
• Antiviral Drug Research: Serves as a precursor in the development of neuraminidase inhibitors and other carbohydrate-based antiviral compounds.
• Glycobiology & Biochemistry: Used in enzymatic studies, metabolic pathway research, and the synthesis of complex oligosaccharides and glycoconjugates.
• Chemical Synthesis: Acts as a versatile building block for creating libraries of iminosugars and azasugars with potential therapeutic activity.
• Standards & Reference Materials: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(3S,4R,5S,6R)-3-Amino-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2,4,5-Triol Hydrochloride
CAS No.	6730-09-2
Molecular Formula	C6H14ClNO5
Molecular Weight	215.63 g/mol
Synonyms	1-Deoxynojirimycin Hydrochloride; DNJ HCl; (3S,4R,5S,6R)-3-Amino-6-(hydroxymethyl)tetrahydro-2H-pyran-2,4,5-triol hydrochloride; D-Gluco-1,5-iminofuranose hydrochloride; Moranoline Hydrochloride; 1,5-Dideoxy-1,5-imino-D-glucitol hydrochloride; (3R,4R,5S,6R)-3-Amino-6-(hydroxymethyl)tetrahydro-2H-pyran-2,4,5-triol hydrochloride
EINECS	229-793-0

Quality Control

Our (3S,4R,5S,6R)-3-Amino-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2,4,5-Triol Hydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed HPLC, NMR, and optical rotation data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.