Description

2-Methyl-3-Nitrobenzotrifluoride is a specialized fluorinated aromatic nitro compound that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and nitro substituents on the methylbenzene backbone make it a valuable intermediate for introducing specific functional groups and modifying electronic properties in target molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic core for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for synthesizing complex, high-performance dyes and pigments with specific color fastness and solubility properties.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex biaryl structures common in many functional molecules.

Basic Information

Product Name	2-Methyl-3-Nitrobenzotrifluoride
CAS No.	6656-49-1
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	1-Methyl-2-nitro-3-(trifluoromethyl)benzene; 3-(Trifluoromethyl)-2-nitrotoluene; 2-Nitro-α,α,α-trifluoro-m-xylene; 2-Methyl-3-nitrobenzotrifluoride; 2-Nitro-3-(trifluoromethyl)toluene; m-Xylene, 2-nitro-α,α,α-trifluoro-; Benzene, 1-methyl-2-nitro-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-Nitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key specifications such as assay, impurity profile, and physical properties. Our quality commitment supports compliance with cGMP and ISO standards for use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.