Description

4-Methylbenzotrifluoride is a versatile fluorinated aromatic building block, valued for its trifluoromethyl group which imparts unique electronic and lipophilic properties to target molecules. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs) where enhanced metabolic stability and bioavailability are required. It serves as a critical intermediate for researchers and manufacturers in the agrochemical, pharmaceutical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a trifluoromethylphenyl moiety to modulate biological activity and pharmacokinetics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances product efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers and epoxy resins to alter surface energy, improve chemical resistance, and enhance material durability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a starting material for synthesizing complex fluorinated aromatic compounds in R&D settings.
• Dye & Pigment Industry: Acts as an intermediate in the production of specialty dyes and pigments, providing improved lightfastness and color properties.

Basic Information

Item	Detail
Product Name	4-Methylbenzotrifluoride
CAS No.	6140-17-6
Molecular Formula	C8H7F3
Molecular Weight	160.14 g/mol
Synonyms	α,α,α-Trifluoro-p-xylene; 1-Methyl-4-(trifluoromethyl)benzene; p-(Trifluoromethyl)toluene; 4-(Trifluoromethyl)toluene; p-Methylbenzotrifluoride; PTFT; 4-Methyl-α,α,α-trifluorotoluene
EINECS	228-100-5

Quality Control

Our 4-Methylbenzotrifluoride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to ISO 9001 standards and can support compliance with REACH and other global regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	1.18 - 1.20 g/mL
Refractive Index (n20D)	1.440 - 1.444

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.