Description

Digoxigenin-3,12-Diacetate is a key acetylated derivative of the cardiac glycoside aglycone, digoxigenin. This high-purity intermediate is critical for the synthesis and research of specialized biochemical probes and pharmaceutical reference standards. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and life science sectors for advanced analytical and developmental work.

Application

• Biochemical Probe Synthesis: A crucial precursor for labeling and detection reagents used in molecular biology and immunohistochemistry.
• Pharmaceutical Reference Standard: Serves as a certified standard for the quality control and assay development of digoxin and related cardiac glycosides.
• Metabolic Pathway Research: Used in studies investigating the biosynthesis and metabolic fate of cardenolide compounds.
• Antibody Conjugation: Employed in the preparation of hapten-carrier protein conjugates for antibody production and immunoassay development.
• Academic & Industrial R&D: A fundamental building block in organic synthesis and medicinal chemistry research for novel therapeutic agents.

Basic Information

Product Name	Digoxigenin-3,12-Diacetate
CAS No.	6078-59-7
Molecular Formula	C28H38O8
Molecular Weight	502.60 g/mol
Synonyms	3β,12β-Diacetoxy-5β,14β-card-20(22)-enolide; Digoxigenin Diacetate; 3,12-Di-O-acetyldigoxigenin; (3β,5β,12β)-3,12-Bis(acetyloxy)-14-hydroxycard-20(22)-enolide; NSC 107919; Digoxigenin 3,12-diacetate; 5β-Card-20(22)-enolide-3β,12β,14-triol 3,12-diacetate
EINECS	Contact for details

Quality Control

Our Digoxigenin-3,12-Diacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.