Description

15-Hydroxy-4-Methylpicrasa-1,13-Diene-3,16-Dione is a specialized diterpenoid quinone methide compound of significant interest in advanced organic synthesis and pharmaceutical research. Its unique molecular scaffold makes it a valuable intermediate for developing novel bioactive molecules and studying structure-activity relationships. This high-purity compound is primarily utilized by research institutions and pharmaceutical companies focused on medicinal chemistry, natural product synthesis, and the development of new therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key synthetic intermediate or reference standard in the discovery and development of new drug candidates, particularly those targeting inflammation or cancer.
• Medicinal Chemistry: Used as a core scaffold or building block for the synthesis of novel analogs to explore and optimize biological activity and pharmacokinetic properties.
• Natural Product Synthesis: Acts as a crucial intermediate in the total or semi-synthesis of complex natural products belonging to the picrasane or related diterpenoid families.
• Biochemical Research: Employed as a tool compound in biochemical assays to investigate specific enzyme interactions or cellular pathways.
• Academic Research: Utilized in university and institutional laboratories for fundamental studies in organic synthesis, chemical biology, and natural product chemistry.
• Reference Standard: Provides a high-purity standard for analytical methods such as HPLC, LC-MS, or NMR in quality control and compound identification workflows.

Basic Information

Product Name	15-Hydroxy-4-Methylpicrasa-1,13-Diene-3,16-Dione
CAS No.	6072-93-1
Molecular Formula	C20H24O4
Molecular Weight	328.40 g/mol
Synonyms	15-Hydroxy-4-methylpicrasa-1,13-dien-3,16-dione; 4-Methyl-15-hydroxypicrasa-1,13-diene-3,16-dione; Picrasane Diterpenoid; Nigakilactone D; (4R,5S,8R,9S,10R,13R)-4,9,10-Trimethyl-14-methylidene-5,8,13,15-tetrakis(oxidanyl)pentacyclo[9.5.1.0¹,⁸.0²,⁷.0¹²,¹⁷]heptadecane-3,16-dione
EINECS	Contact for details

Quality Control

Our 15-Hydroxy-4-Methylpicrasa-1,13-Diene-3,16-Dione is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under inert atmosphere at lower temperatures (e.g., -20°C) to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.