Description

Methionylpuromycin is a specialized puromycin derivative, a compound of significant interest in biochemical and pharmacological research. Its primary value lies in its role as a potent inhibitor of protein synthesis, making it a critical tool for studying ribosomal function and cellular processes. This product is essential for researchers and developers in the fields of molecular biology, antibiotic mechanism studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a specific inhibitor to study protein synthesis mechanisms in cell-free systems and in vivo models.
• Antibiotic Mechanism Studies: Serves as a key reference compound for investigating the action of aminonucleoside antibiotics on the peptidyl transferase center of the ribosome.
• Cell Biology: Employed in experiments to selectively terminate translation, enabling the study of mRNA stability, protein half-life, and gene expression regulation.
• Pharmaceutical Development: Acts as a starting material or intermediate in the research and development of novel antimicrobial and anticancer agents targeting protein synthesis.
• Diagnostic Tool Development: Utilized in the creation of assays to screen for compounds that can overcome or modulate ribosomal inhibition.

Basic Information

Product Name	Methionylpuromycin
CAS No.	6042-08-6
Molecular Formula	C28H39N7O7S
Molecular Weight	617.73 g/mol
Synonyms	N-[(3S)-3-Amino-3-carboxypropyl]-N-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-2-amino-4-methylsulfanylbutanamide; L-Methionylpuromycin; Methionyl-Puromycin; Puromycin, methionyl-; NSC 329856; O-Methionylpuromycin
EINECS	Contact for details

Quality Control

Our Methionylpuromycin is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable performance in your experimental systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.