Description

2,6-Difluorobenzyl Chloride is a versatile fluorinated benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the aromatic ring, which significantly influences the electronic properties and metabolic stability of final compounds. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, oncology, and anti-infectives.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, where the difluoro moiety enhances lipophilicity and biological efficacy.
• Liquid Crystal Materials: Used in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for electron-transport or host materials in OLED devices.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and specialty chemicals.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2,6-Difluorobenzyl Chloride
CAS No.	697-73-4
Molecular Formula	C7H5ClF2
Molecular Weight	162.56 g/mol
Synonyms	α-Chloro-2,6-difluorotoluene; (2,6-Difluorophenyl)methyl chloride; 2,6-Difluorobenzylchloride; 1-(Chloromethyl)-2,6-difluorobenzene; 2,6-Difluoro-α-chlorotoluene; Benzene, 1-(chloromethyl)-2,6-difluoro-; 2,6-Difluorobenzyl Chloride; 2,6-DFBC
EINECS	211-806-8

Quality Control

Our 2,6-Difluorobenzyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Density (at 20°C)	1.30 - 1.35 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.