Description

2,4,6-Trifluoropyrimidine CAS NO 696-82-2 is a versatile fluorinated heterocyclic building block prized for its unique reactivity profile. This compound is essential for introducing the pyrimidine scaffold with fluorine substituents, enabling fine-tuning of electronic and steric properties in target molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and electronic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic aromatic substitution, and as a scaffold for constructing complex heterocyclic systems in medicinal chemistry.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and developing new fluorination methodologies in academic and industrial R&D.

Basic Information

Product Name	2,4,6-Trifluoropyrimidine
CAS No.	696-82-2
Molecular Formula	C4HF3N2
Molecular Weight	134.06 g/mol
Synonyms	2,4,6-Trifluoropyrimidine; Pyrimidine, 2,4,6-trifluoro-; s-Triazinetrifluoride; 2,4,6-Trifluoro-1,3-diazine; 1,3-Diazine, 2,4,6-trifluoro-; NSC 5239; 696-82-2 (CAS); Trifluoropyrimidine
EINECS	211-799-6

Quality Control

Our 2,4,6-Trifluoropyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and highly volatile nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.