Description

3-Fluoropyridine n-Oxide is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a fluorine substituent and an N-oxide moiety, makes it a valuable precursor for the development of pharmaceuticals, agrochemicals, and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and fine chemical industries for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infective agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Employed in the synthesis of fluorinated liquid crystals, polymers, and electronic materials for specialized applications.
• Chemical Derivatization: The reactive N-oxide group allows for further functionalization, enabling the introduction of various substituents onto the pyridine ring.
• Academic & Industrial R&D: A fundamental research chemical for exploring new fluorination reactions and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	3-Fluoropyridine n-Oxide
CAS No.	695-37-4
Molecular Formula	C5H4FNO
Molecular Weight	113.09 g/mol
Synonyms	3-Fluoropyridine 1-Oxide; 3-Fluoropyridine N-Oxide; 3-Fluoropyridine Oxide; Pyridine, 3-fluoro-, 1-oxide; 3-Fluoropyridinium-1-olate; 3-Fluoro-1-oxidopyridin-1-ium
EINECS	Contact for details

Quality Control

Our 3-Fluoropyridine n-Oxide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.