Description

5-Fluoropyrimidine is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis and pharmaceutical research. Its core value lies in the strategic introduction of a fluorine atom into the pyrimidine scaffold, enabling the fine-tuning of biological activity, metabolic stability, and physicochemical properties in target molecules. This high-purity intermediate is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated nucleoside analogs, antiviral agents, and anticancer drugs.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides and herbicides with enhanced efficacy and environmental profiles.
• Chemical Research: Serves as a fundamental building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: Employed in methodological research to study fluorination reactions and the properties of fluorinated heterocycles.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and electronic materials requiring fluorinated components.

Basic Information

Product Name	5-Fluoropyrimidine
CAS No.	675-21-8
Molecular Formula	C4H3FN2
Molecular Weight	98.08 g/mol
Synonyms	5-Fluoropyrimidine; Fluoropyrimidine; 5-Fluoro-1,3-diazine; 5-Fluoro-pyrimidine; Pyrimidine, 5-fluoro-; 675-21-8; 5-Fluor-1,3-diazin
EINECS	211-625-8

Quality Control

Our 5-Fluoropyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to confirm identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.