Description

p-Trifluoromethoxybenzaldehyde is a high-purity aromatic aldehyde building block characterized by its trifluoromethoxy substituent. This compound is valued for its unique electronic properties and stability, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers and epoxy resins to impart specific characteristics such as enhanced chemical resistance, thermal stability, or altered surface properties.
• Organic Synthesis & Catalysis: Employed as a versatile reagent in cross-coupling reactions, asymmetric synthesis, and as a ligand precursor in organometallic catalysis.
• Flavor & Fragrance Chemistry: Used in the research and development of novel aromatic compounds for high-value fragrance and flavor applications.

Basic Information

Product Name	p-Trifluoromethoxybenzaldehyde
CAS No.	659-86-8
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	4-(Trifluoromethoxy)benzaldehyde; 4-Trifluoromethoxybenzaldehyde; α-Oxo-4-(trifluoromethoxy)toluene; Benzaldehyde, 4-(trifluoromethoxy)-; p-(Trifluoromethoxy)benzaldehyde; 1-Formyl-4-(trifluoromethoxy)benzene; 4-Formylphenyl trifluoromethyl ether
EINECS	Contact for details

Quality Control

Our p-Trifluoromethoxybenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.