Description

3-[(2-Chloroacetyl)Amino]Benzenesulfonyl Fluoride is a versatile and highly reactive chemical intermediate, primarily valued for its sulfonyl fluoride and chloroacetyl functional groups. This compound is critical for the synthesis of more complex molecules, particularly in the development of pharmaceuticals and agrochemicals. It is essential for research institutions and industrial manufacturers engaged in medicinal chemistry, proteomics research, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of sulfonamide-based drugs and other bioactive molecules.
• Chemical Biology & Proteomics: Used as a reactive probe in activity-based protein profiling (ABPP) due to the sulfonyl fluoride warhead's ability to covalently modify specific amino acids.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of herbicides and fungicides containing benzenesulfonyl motifs.
• Material Science Research: Employed in the development of novel polymers and functional materials through its reactive sites.
• Organic Synthesis Reagent: Utilized in various coupling reactions and as a precursor for introducing the sulfonyl fluoride group into target molecules.

Basic Information

Product Name	3-[(2-Chloroacetyl)Amino]Benzenesulfonyl Fluoride
CAS No.	658-97-9
Molecular Formula	C8H7ClFNO3S
Molecular Weight	251.66 g/mol
Synonyms	N-(3-Fluorosulfonylphenyl)-2-chloroacetamide; 2-Chloro-N-(3-fluorosulfonylphenyl)acetamide; 3-(2-Chloroacetamido)benzenesulfonyl Fluoride; Benzenesulfonyl fluoride, 3-[(2-chloroacetyl)amino]-; 3-Amino-N-chloroacetylbenzenesulfonyl Fluoride
EINECS	Contact for details

Quality Control

Our production of 3-[(2-Chloroacetyl)Amino]Benzenesulfonyl Fluoride adheres to stringent quality management protocols. Every batch is analyzed to ensure high purity and consistency, with specifications meeting the rigorous demands of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.