Description

L-Phenylalanine-Ul-14C is a uniformly carbon-14 labeled isotopologue of the essential amino acid L-Phenylalanine, identified by CAS NO 658-69-5. This radiolabeled compound is a critical tool for metabolic pathway tracing, pharmacokinetic studies, and protein synthesis research, offering unparalleled precision in tracking biochemical fate. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in advanced drug development and biochemical mechanism elucidation.

Application

• Tracer Studies in Metabolism Research: Used to investigate the metabolic pathways and catabolism of phenylalanine in vivo and in vitro.
• Drug Metabolism and Pharmacokinetics (DMPK): Essential for ADME (Absorption, Distribution, Metabolism, Excretion) studies of new pharmaceutical compounds.
• Protein and Peptide Labeling: Incorporated into proteins and peptides for tracking synthesis, turnover, and localization.
• Biomedical Research: Applied in studies related to metabolic disorders such as Phenylketonuria (PKU).
• Plant and Microbial Biochemistry: Utilized to study the shikimate pathway and aromatic amino acid biosynthesis.
• Radiochemical Synthesis: Serves as a labeled precursor for the synthesis of more complex radiolabeled molecules.

Basic Information

Item	Details
Product Name	L-Phenylalanine-Ul-14C
CAS No.	658-69-5
Molecular Formula	C9H1114CNO2 (or C9H11NO2 with all carbons as 14C)
Molecular Weight	Contact for details (varies with specific activity)
Synonyms	(S)-2-Amino-3-phenylpropanoic acid-U-14C; L-α-Amino-β-phenylpropionic acid-U-14C; Phenylalanine (U-14C); L-Phe-14C(U); F-U-14C; Uniformly Labeled Carbon-14 L-Phenylalanine; [U-14C]-L-Phenylalanine
EINECS	Contact for details

Quality Control

Every batch of L-Phenylalanine-Ul-14C is manufactured and analyzed under strict quality systems. The product undergoes rigorous testing to ensure compliance with high-purity standards for radiochemicals, including verification of radiochemical purity, specific activity, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing analytical methods (HPLC, TLC, MS) and results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep the container sealed under an inert atmosphere in a dedicated freezer. Follow all applicable radiation safety guidelines for handling and storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / MS)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (HPLC)	≥ 98%
Specific Activity	Contact for details (mCi/mmol)
Solvent (if supplied as solution)	Specified on COA
Radioactivity Concentration	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.