Description

Antimycin A1 is a potent secondary metabolite and a specific inhibitor of mitochondrial electron transport, widely recognized for its role in biochemical research. This compound is critical for studying cellular respiration, apoptosis, and energy metabolism pathways in both academic and industrial R&D settings. It is essential for researchers and manufacturers in the fields of life sciences, biochemistry, and pharmaceutical development who require high-purity biochemical tools.

Application

• Biochemical Research: As a specific inhibitor of complex III (cytochrome bc1 complex) in the mitochondrial electron transport chain.
• Apoptosis Studies: Used to induce apoptosis in cell culture models by disrupting mitochondrial function.
• Metabolic Pathway Analysis: A key tool for investigating cellular bioenergetics, ATP production, and oxidative phosphorylation.
• Antifungal Agent Research: Serves as a reference standard and active component in studies of antifungal mechanisms.
• Insecticide and Pesticide Research: Used in biochemical assays to study its mode of action as a natural pesticide.
• Pharmaceutical Screening: Employed in high-throughput screening assays to identify compounds that modulate mitochondrial function.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.

Basic Information

Product Name	Antimycin A1
CAS No.	642-15-9
Molecular Formula	C28H40N2O9
Molecular Weight	548.63 g/mol
Synonyms	Antimycin A; Antimycin A1; Antipiricullin; Blastmycin; Virosin; NSC 13386; UNII-64215UG9XY; 3-[(2R,3S,6S,7R,8R)-3-[(2S,3S,6S)-3-Formamido-2,6-dimethyl-4-oxooct-7-en-1-yl]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-8-yl]salicylic acid
EINECS	211-400-4

Quality Control

Our Antimycin A1 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	-70° to -80° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.