Description

3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-5,12β,14-Trihydroxy-19-Oxo-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its specific stereochemistry and functional groups, which are essential for producing targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of cardiovascular drugs and other specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel cardiac glycosides and related therapeutic compounds.
• Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na⁺/K⁺-ATPase) inhibition and cardiac cell signaling pathways.
• API Development: Employed in the research and development of Active Pharmaceutical Ingredients (APIs) targeting heart failure and certain arrhythmias.
• Preclinical Studies: Utilized in pharmacological and toxicological testing during the drug discovery process.
• Academic Research: Supports university and institutional research in medicinal chemistry and pharmacology.

Basic Information

Product Name	3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-5,12β,14-Trihydroxy-19-Oxo-5β-Card-20(22)-Enolide
CAS No.	639-13-4
Molecular Formula	C₂₉H₄₄O₁₂
Molecular Weight	596.66 g/mol
Synonyms	Digitoxigenin α-L-diginoside; 3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,12β,14-trihydroxy-19-oxo-5β-card-20(22)-enolide; α-Acetyldigitoxin; α-Acetyldigoxin impurity; 3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide-19-one; Acetyldigitoxin α; Digitoxigenin α-L-acetyldigitoxoside
EINECS	Contact for details

Quality Control

Our 3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-5,12β,14-Trihydroxy-19-Oxo-5β-Card-20(22)-Enolide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.