Description

Pyridoxal-5-Phosphate Semicarbazone is a chemically modified derivative of the biologically essential coenzyme pyridoxal 5'-phosphate (PLP). This compound is valued for its role as a stable, specific inhibitor and analytical tool in the study of PLP-dependent enzymatic systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical and life science sectors for biochemical research, enzyme mechanism studies, and as a reference standard in analytical applications.

Application

• Biochemical Research: Used as a specific inhibitor to study the mechanism and kinetics of pyridoxal 5'-phosphate (PLP)-dependent enzymes, such as transaminases and decarboxylases.
• Enzymology Studies: Serves as a stable analog of PLP to probe active sites and understand cofactor binding and catalysis.
• Pharmaceutical Development: Employed in early-stage research for investigating metabolic pathways and potential drug targets related to vitamin B6 metabolism.
• Analytical Reference Standard: Used in high-performance liquid chromatography (HPLC) and other analytical methods for the qualification and quantification of related compounds.
• Diagnostic Reagent Manufacturing: A potential component in the formulation of specialized diagnostic kits for clinical chemistry applications.

Basic Information

Product Name	Pyridoxal-5-Phosphate Semicarbazone
CAS No.	634-27-5
Molecular Formula	C11H16N4O7P
Molecular Weight	347.24 g/mol
Synonyms	Pyridoxal 5'-Phosphate Semicarbazone; PLP Semicarbazone; 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-Phosphate Semicarbazone; 4-Formyl-3-hydroxy-5-hydroxymethyl-2-methylpyridine 5-Phosphate Semicarbazone; Vitamin B6 Phosphate Semicarbazone; P5P Semicarbazone; Pyridoxal Phosphate Semicarbazone
EINECS	Contact for details

Quality Control

Our Pyridoxal-5-Phosphate Semicarbazone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and verification of physical properties. We ensure compliance with relevant standards for research-grade chemicals. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.