Description

n-Nitrosodi-n-Propylamine is a nitrosamine compound of significant interest in industrial research and analytical chemistry. Its primary commercial value lies in its critical role as a certified reference material and analytical standard for quality control and safety testing. This compound is essential for laboratories and manufacturers requiring precise calibration for the detection and quantification of nitrosamine impurities, particularly in pharmaceuticals, agrochemicals, and consumer products.

Application

• Analytical Reference Standard: Primary use as a high-purity certified material for calibrating equipment (GC, LC-MS) in nitrosamine impurity testing.
• Pharmaceutical Research: Critical for method development and validation to ensure compliance with stringent regulatory limits (e.g., EMA, FDA) on nitrosamine genotoxic impurities in APIs and finished drug products.
• Toxicological & Environmental Studies: Serves as a key reagent in research investigating the metabolism, carcinogenicity, and environmental fate of N-nitrosamines.
• Quality Assurance in Manufacturing: Used in the internal quality control labs of chemical and material producers to monitor for unintended nitrosamine formation.
• Food and Consumer Safety Testing: Employed in trace analysis methods to detect nitrosamines in foodstuffs, cosmetics, and rubber products.
• Method Transfer and Proficiency Testing: Acts as a benchmark compound for inter-laboratory comparisons and accreditation audits.

Basic Information

Product Name	n-Nitrosodi-n-Propylamine
CAS No.	621-64-7
Molecular Formula	C6H14N2O
Molecular Weight	130.19 g/mol
Synonyms	N-Nitrosodi-n-propylamine; NDPA; Di-n-propylnitrosamine; N-Nitroso-N-dipropylamine; N-Nitrosodipropylamine; 1-Propanamine, N-nitroso-N-propyl-; Nitrosodipropylamine; DNPA
EINECS	210-698-4

Quality Control

Every batch of our n-Nitrosodi-n-Propylamine is manufactured and handled under strict quality management systems. The product undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for use as a reference material. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and traceability is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at controlled room temperature (15-25°C). Due to its light-sensitive and highly volatile nature, minimize exposure to air and handle in a fume hood. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Clear, yellow to amber liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.