Description

1-Isopropoxy-3-Trifluoromethyl-Benzene is a high-purity aromatic ether derivative, valued for its unique trifluoromethyl and isopropoxy functional groups. This compound serves as a versatile and critical building block in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoromethylated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Employed to introduce fluorine-containing side chains into polymers, altering their surface properties, chemical resistance, and thermal stability.
• Cross-Coupling Reactions: Serves as a reliable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex biaryl structures.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and developing novel synthetic pathways in academic and industrial labs.

Basic Information

Product Name	1-Isopropoxy-3-Trifluoromethyl-Benzene
CAS No.	621-47-6
Molecular Formula	C10H11F3O
Molecular Weight	204.19 g/mol
Synonyms	3-(Trifluoromethyl)phenyl isopropyl ether; m-Trifluoromethylphenyl isopropyl ether; Isopropyl 3-(trifluoromethyl)phenyl ether; 3-Isopropoxybenzotrifluoride; 1-Isopropoxy-3-(trifluoromethyl)benzene; 3-Trifluoromethylphenyl isopropyl ether; α,α,α-Trifluoro-m-isopropoxytoluene
EINECS	Contact for details

Quality Control

Our 1-Isopropoxy-3-Trifluoromethyl-Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and fluorides. Recommended storage temperature is 2-25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total
Density (20°C)	~1.15 g/cm³
Refractive Index (n20D)	~1.430 - 1.450

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.