Description

2,4-Dimethylbenzenesulfonyl Chloride is a versatile and reactive organosulfur compound widely used as a key sulfonylation reagent and synthetic intermediate. Its primary value lies in its ability to introduce the sulfonyl functional group into target molecules, enabling the synthesis of sulfonamides, sulfonate esters, and other derivatives critical for advanced chemical manufacturing. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a building block for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing sulfonamide-based drugs, including diuretics, antibacterial agents, and protease inhibitors.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require the sulfonyl moiety for biological activity.
• Dyestuff and Pigment Manufacturing: Acts as a sulfonating agent to create sulfonated dyes and pigments, improving their solubility and application properties.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and resins, such as sulfonated polymers for ion-exchange membranes.
• Chemical Research & Development: Serves as a standard reagent in organic synthesis laboratories for method development and creating novel sulfonyl compounds.
• Liquid Crystal and Electronic Material Precursor: Used in the synthesis of sulfonyl-containing compounds for advanced materials in display and semiconductor applications.

Basic Information

Product Name	2,4-Dimethylbenzenesulfonyl Chloride
CAS No.	609-60-9
Molecular Formula	C8H9ClO2S
Molecular Weight	204.67 g/mol
Synonyms	2,4-Dimethylbenzenesulfonyl chloride; 2,4-Xylenesulfonyl chloride; p-Toluenesulfonyl chloride, 2,4-dimethyl-; 2,4-Dimethylphenylsulfonyl chloride; 2,4-Dimethylbenzene-1-sulfonyl chloride; NSC 403119; 1-(Chlorosulfonyl)-2,4-dimethylbenzene; 2,4-Dimethyl-1-sulfonylchlorobenzene
EINECS	210-200-1

Quality Control

Our 2,4-Dimethylbenzenesulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material is suitable for demanding applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, strong oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or lumps
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40°C - 44°C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.