Description

Actidione is a potent, naturally occurring antibiotic and fungicide, also known chemically as cycloheximide. This compound is valued for its specific and powerful inhibitory action against eukaryotic protein synthesis, making it a critical tool in research and industrial applications. It is essential for professionals in agricultural research, microbiology, and biotechnology who require a reliable agent for fungal control, selection in cell culture, and biochemical studies. Actidione CAS NO 66-81-9 is supplied to meet the stringent demands of these fields.

Application

• Agricultural Research & Fungicide: Used as a selective agent in plant pathology research and as a model compound for studying antifungal mechanisms.
• Microbiological & Cell Culture: Employed in laboratory settings for the selection of yeast and fungal strains, and to inhibit protein synthesis in eukaryotic cell cultures.
• Biochemical Research: Serves as a potent inhibitor in studies of ribosome function and translational mechanisms in eukaryotes.
• Plant Tissue Culture: Acts as an additive in media to suppress fungal contamination without harming plant cells at controlled concentrations.
• Preservative Studies: Investigated for its potential in protecting materials like wood, leather, and paints from fungal degradation.
• Pharmaceutical Intermediates: Used in the synthesis and research of more complex pharmaceutical compounds.

Basic Information

Product Name	Actidione
CAS No.	66-81-9
Molecular Formula	C15H23NO4
Molecular Weight	281.35 g/mol
Synonyms	Cycloheximide; Naramycin A; Acti-dione; 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide; U 4527; NSC 185; Hizarocin; Kaken; Neocycloheximide
EINECS	200-636-0

Quality Control

Our Actidione is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure high purity and consistency, with specifications typically meeting or exceeding standard laboratory and research-grade requirements. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details
Solubility	Soluble in ethanol, methanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.