Description

Proadifen Hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a potent, non-selective inhibitor of cytochrome P450 enzymes, making it a critical tool in drug metabolism and pharmacokinetic (DMPK) studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and chemical manufacturers engaged in the synthesis of specialized fine chemicals.

Application

• Pharmacological Research: Used extensively as a cytochrome P450 (CYP) enzyme inhibitor to study drug-drug interactions and metabolic pathways in preclinical research.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex bioactive molecules and reference standards.
• Biochemical Tool Compound: Employed in in vitro assays to elucidate the role of specific CYP isoforms in the metabolism of new chemical entities.
• Metabolism Studies: A standard reagent for modulating enzymatic activity to identify primary routes of biotransformation for candidate drugs.
• Academic & Clinical Research: Supports fundamental research in toxicology, enzymology, and the mechanisms of chemical biological interactions.

Basic Information

Product Name	Proadifen Hydrochloride
CAS No.	62-68-0
Molecular Formula	C20H24N2O • HCl
Molecular Weight	344.88 g/mol
Synonyms	SKF-525A Hydrochloride; 2-(Diethylamino)ethyl 2,2-diphenylpentanoate hydrochloride; β-Diethylaminoethyldiphenylpropylacetate Hydrochloride; Diphenylpropylacetic Acid β-Diethylaminoethyl Ester Hydrochloride; Proadifen HCl; SKF 525-A
EINECS	200-543-1

Quality Control

Our Proadifen Hydrochloride is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing specifications and results. We can supply material suitable for research and development purposes, with quality standards aligned with industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.